#27: Melissa McCarthy as The Queen of Hearts from Alice in Wonderland
You can’t discuss Alice in Wonderland without mentioning Alice or The Queen of Hearts. The Queen’s role is vital to the ending of the movie, but if Disney decided on a mini-series with each of Wonderland’s eccentric characters, the Queen’s story arc would be on our must-watch list.

The chaotic, almost bipolar nature of the Queen of Hearts can be reined in by Melissa McCarthy for a more mature focus on Alice in Wonderland. McCarthy is a shoo-in for the role since she has already done the work of Ursula in Disney’s upcoming The Little Mermaid remake.