False equivalence
Along with this claim that the use of Karen is a slur, some white women have argued that it’s just like using the N-word, and so should be stopped immediately. As our adorable yellow genius Lisa Simpson points out in her illustrated TED talk this is rubbish. She nicely explains the false equivalence.
Using the word Karen to gently mock the behavior of people who think they are the center of the universe is slightly different than denigrating a whole race. Even the most entitled Karens can’t think this is a sensible argument. Or, then again, maybe they can, and they want to see your manager.