What’s going on here?
In Endgame, Captain America picks up Mjolnir, and it’s a big deal for everyone. In truth, it is a pretty huge deal. In Norse mythology, there are several stories where fantastical beings steal his belongings, forcing him to get them back. But those that can pick Mjolnir up are worthy of possessing his powers.
Imagine being Thanos in that situation. You have no prior knowledge of Norse mythology, nor do you understand what makes Mjolnir such a big deal. This photoshopped version of confused Pikachu pretty much sums up what Thanos would’ve been feeling at the time. Meanwhile, the rest of us had surprised Pikachu plastered on our faces.